전체 8345
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- Communicating Science: Tools for Scientists and Engineers
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- - Tiffany Lohwater, Public Engagement Manager, AAAS (2010/11/18)
- - Category : Career Development/OITE
- Objective: Scientists and engineers who foster information-sharing and respect between science and the public are essential for the public communication of and engagement with sicnece. Communication is typically and acquired, not innate skill, and the American Association for the Advancement of Science (AAAS) maintains that scientists should be provided with quality resource to help develop their public communication and outreach skills. Further, scientists are increasingly required by funding agencies to extend beyond the scientific community and communicate their research directly to the greater public, including the media and policy makers, but traditional scientific training typically does not prepare scientists to be effective public communicators.
The AAAS Center for Public Engagement with Science and Technology has developed workshops and a website for scientists and enginers who communicate scient with Public audiences. Communicating Science: Tools for Scientists and Engineers: seeks to provide researchers with communication resources through in-person workshops and online materials. Visit www.aaas.org/communicating science for webinars, how-to=tips, and additional resources.
http://www.training.nih.gov
Communicating Science: Tools for Scientists and Engineers
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- Globalization and Health: The Role of Knowledge in an Interdependent World
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- - Dr. Julio Frenk (2010/11/18)
- - Category : David E. Barmes
- 2009 David E. Barmes Global Health Lecture
Dr. Julio Frenk, recipient of the 2008 Clinton Global Citizen Award for changing ？？？the way practitioners and policy makers across the world think about health,？？？ previously served as the Minister of Health of Mexico from 2000 to 2006. During his tenure he introduced a program of comprehensive national health insurance, known as Seguro Popular, which expanded access to health care for tens of millions of previously uninsured Mexicans. He also was a senior fellow in the global health program of the Bill & Melinda Gates Foundation.
NIH Director Francis S. Collins will deliver introductory remarks at the Barmes Lecture. Dr. Collins has identified global health as a top priority and has singled it out as one of the five areas he wants to focus on during his tenure.
The annual Barmes Lecture honors the late David E. Barmes, special expert for international health at the NIDCR. Prior to joining NIDCR, he served in senior management positions related to oral health, health promotion, and non-communicable diseases at the World Health Organization in Geneva.
http://www.nidcr.nih.gov/NewsAndFeatures/Announcements/Barmes2009.htm
Globalization and Health: The Role of Knowledge in an Interdependent World
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- Give Them Something to Talk About: Public Speaking with Poise, Punch, and Purpose (HHS-Only)
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- - Lisa Moeller, Nicole Fleisher, Beth Stinson (2010/11/18)
- - Category : GMAC (HHS Only)
- A GMAC Subcommittee on Training Seminar on How to Give a Presentation for the Grants Management Community.
New Years is coming ？？？ time to make those resolutions. Start with a bang! This could be your year to conquer your public speaking goal. If you want to razzle-dazzle your audience but feel like you？？？re coming up short, this is the session for you! Both the novice and advanced speaker will learn new techniques for effective presentations. Rewire your thinking process to ensure you start and finish your goal, design presentations that are effective and engaging, and use PowerPoint for maximum impact. Walk away feeling empowered that this will be a resolution that you can keep!
http://odoerdb2.od.nih.gov/gmac/gmac/trs_flyer_20091215.html
Give Them Something to Talk About: Public Speaking with Poise, Punch, and Purpose (HHS-Only)
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- IMAG Futures Meeting - Day 2
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- - Interagency Modeling and Analysis Group (IMAG) (2010/11/18)
- - Category : Conferences
- This roundtable discussion is an opportunity to assess to what extent computational modeling has succeeded or failed to make a difference in the broader research endeavor, and to discuss these issues in the context of current challenges and opportunities for biomedical, biological and behavioral modeling.
Meeting discussions will be grouped by five biological scales:- Population
- Whole-Body
- Cell-Tissue-Organ
- Pathways and Networks
- Atomic and Molecular
IMAG Futures Meeting - Day 2
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- From Cell Phones to Cell Biology: High Tech, Low Cost Solutions for Global Health
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- - Richards-Kortum, Rebecca.
National Institutes of Health (U.S.) (2010/11/18) - - Category : Wednesday Afternoon Lectures
- - Richards-Kortum, Rebecca.
- Advances in the biosciences and public health are responsible for dramatic gains in life expectancy achieved over the last century. Yet, the majority of the world has not benefited from this progress. Sustainable and scalable innovations to prevent disease are needed. This talk will describe efforts of bioengineering faculty and students to develop new diagnostic and therapeutic tools which can be used at the point-of-care (POC) to improve health in low resource settings.
Advances in MEMS technologies, molecular recognition, and low power sensors now offer the ability to design low-cost, reusable platforms for POC diagnostics. Efforts to integrate molecular imaging together with miniature microscopes are now yielding new POC diagnostics for infectious and chronic diseases. Driven by advances in consumer electronics, high resolution imaging can be obtained with low cost devices; advances in digital signal processing provide the ability to automate analysis.
In parallel, multidisciplinary educational programs are engaging undergraduate students to address POC design problems in developing countries. In creating solutions to real world challenges, students are challenged to think beyond traditional disciplinary and geographic boundaries.
The NIH Directors Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.
From Cell Phones to Cell Biology: High Tech, Low Cost Solutions for Global Health
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- OHR All Hands Meeting - December 2009 (NIH-Only)
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- - Christine Major, OHR Director and supporting staff; Dr. Francis Collins, NIH Director/Colleen Barros (TBD) (2010/11/18)
- - Category : Human Resources (NIH Only)
- For more information, visit:
OHR All Hands Meeting - December 2009 (NIH-Only)
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- NBS GovTrip HPOC Meeting (NIH-Only)
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- - Jennifer Martin (2010/11/18)
- - Category : Travel (NIH Only)
- Forum for HPOCs to discuss challenges with GovTrip and share ideas on mitigation strategies. GovTrip team will also discuss key functional areas and demo specific exercises.
NBS GovTrip HPOC Meeting (NIH-Only)
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- Ninth Annual John Doppman Memorial Lecture: CTA and 3-D Visualization: Its Evolving Role in Oncologic Imaging
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- - Fishman, Elliot K.
National Institutes of Health (U.S.). Clinical Center. (2010/11/18) - - Category : Clinical Center Grand Rounds
- - Fishman, Elliot K.
- Elliot K. Fishman, MD,
Professor of Radiology and Oncology, Johns Hopkins University School of Medicine,
Director, Division of Diagnostic Imaging,
Director, Division of Abdominal Imaging and Computed Body Tomography, The Johns Hopkins Hospital
For more information, visit
http://www.cc.nih.gov/about/news/grcurrent.html
Ninth Annual John Doppman Memorial Lecture: CTA and 3-D Visualization: Its Evolving Role in Oncologic Imaging
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- Youth Regional Treatment Centers in Indian Country
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- - Pardue, Kim B.
National Institutes of Health (U.S.) (2010/11/18) - - Category : CMS - Centers for Medicare & Medicaid Services
- - Pardue, Kim B.
- Experts from the Youth Regional Treatment Centers will cover:
- YRTC services provided to American Indian and Alaska Native youth
- Success stories
- Challenges encountered and recommended solutions
- David Nolley, CMS, Office of External Affairs;
- Tom Eagle Staff, Nevada Skies YRTC;
- Anthony Yepa, New Sunrise YRTC;
- Angie Wilson, Wemble House YRTC:
- Zella Weaver, Shiprock YRTC;
- Albert Long, Shiprock YRTC;
- Parcae Soule, Ravens Way YRTC;
- Vickie Claymore LaHammer, IHS Aberdeen Area
Youth Regional Treatment Centers in Indian Country
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- Concentrating the fury of somatic hypermutation to immunoglobulin genes
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- - Gearhart, P J.
National Institutes of Health (U.S.). Immunology Interest Group. (2010/11/18) - - Category : Immunology
- - Gearhart, P J.
- Dr. Patricia Gearhart received her Ph.D. in immunology from the University of Pennsylvania in 1974. She performed postdoctoral training at the Johns Hopkins University and was a staff associate at the Carnegie Institution of Washington until 1982. She then became a faculty member, and part of the Immunology Training Program, at the Johns Hopkins University until 1995, when, to the great fortune of the NIH, she moved to the National Institute on Aging. One of the most enigmatic questions in immunology is how the activation-induced deaminase (AID) protein is directed to a very small region of DNA in the immunoglobulin loci, where it causes mutation at a frequency that is a million times greater than in other genes. The purpose of this mutagenic fury is to generate high affinity antibodies and different heavy chain classes. Pat？？？s lab has used biochemical and genetic techniques to study this fascinating process that is initiated when the activation-induced cytidine deaminase (AID) protein deaminates cytosine in DNA to uracil. First, she and her colleagues demonstrated that uracil is present in the DNA of bacterial cells that express the AID protein. Using quantitative Southern and ligation-mediated PCR techniques, uracils were detected in actively transcribed genes. The uracils were made predominantly on the nontranscribed strand, in accord with the notion that AID acts on single-stranded DNA. Second, they have studied the spectra of mutations in mice lacking mismatch repair proteins and low-fidelity DNA polymerases. Mice deficient for the Msh2-Msh6 heterodimer and DNA polymerase eta have fewer mutations of A:T base pairs, whereas mutations of C:G base pairs can be directly caused by replication or repair of the uracils. Third, using biochemical techniques Pat has demonstrated that the uracil base is recognized by Msh2-Msh6, which then recruits DNA polymerase eta and stimulates its catalytic activity. Thus, synthesis of DNA by this error-prone polymerase can generate mutations downstream of the uracils, including mutations at A:T base pairs. Finally, a major question in antibody diversity concerns how hypemutation is targeted to the immunoglobulin loci, and is not found elsewhere in DNA from B cells. Mutations are localized to two distinct regions: two kilobases of DNA surrounding and including the rearranged variable gene, and four kilobases of DNA encompassing the switch regions. These regions are downstream of promoters, suggesting that transcription is involved in bringing AID to the locus. To address this question, Pats lab is studying how transcription factors interact with the various enzymes involved in the hypermutation pathway. Understanding this process impacts not only immunology but also cancer biology as it is clear that mis-directed hypermutation can cause lymphomas. Through Pats work it soon may be possible to assemble all the pieces of the enigmatic hypermutation puzzle. Pat is a keen scientist and exciting speaker. Come catch her enthusiasm for immunology!
http://www.grc.nia.nih.gov/branches/lmg/pgearhart.htm
The Immunology Interest Group
Concentrating the fury of somatic hypermutation to immunoglobulin genes
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- All Work and No Play? The Health Benefits of Play
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- - Carol Torgan PhD (2010/11/18)
- - Category : Focus on You Wellness
- Focus on You Wellness Lecture Series. Featuring NIH Executives sharing and discussing their thoughts on striking a balance between work and wellness.
All Work and No Play? The Health Benefits of Play
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- Breast Cancer and Social Interactions: Identifying Multiple Environments that Regulate Gene Expression
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- - Gehlert, Sarah.
National Institutes of Health (U.S.). Office of Behavioral and Social Sciences Research. (2010/11/18) - - Category : BSSR Lecture Series
- - Gehlert, Sarah.
- This lecture is an installment of the Behavioral and Social Sciences Research Lecture Series sponsored by the NIH Office of Behavioral and Social Sciences Research and organized by the NIH Behavioral and Social Sciences Research Coordinating Committee.
The Behavioral and Social Sciences Research Coordinating Committee (BSSR CC), with support from the Office of Behavioral and Social Sciences Research (OBSSR), convenes a series of guest lectures and symposia on selected topics in the behavioral and social sciences. These presentations by prominent behavioral and social scientists provide the NIH community with overviews of current research on topics of scientific and social interest. The lectures and symposia are approximately 50 minutes in length, with additional time for questions and discussion. All seminars are open to NIH staff and to the general public.
BACKGROUND: Though mortality from breast cancer on the whole has declined over the past 15 years, the risk of African-American women dying from the disease is 37 percent higher than that of white women. Previous explanations have considered the role of environmental (social and ecological) and genetic factors separately. However, because 70-80 percent of breast cancers are due to sporadic rather than hereditary mutations, it is important to understand the social and ecological factors that influence sporadic mutations. The current research conducted at the Center for Interdisciplinary Health Disparities Research (CIHDR) explores the connection between genes and environment by utilizing a downward causal model developed by the transdisciplinary research team in which social environmental factors ultimately impact genetic expression of breast cancer through psychosocial factors such as social isolation, depression, and acquired vigilance, and biological processes.
METHOD: The team uses animal models and interviews with newly-diagnosed African American women of a variety of socioeconomic backgrounds in a mutually-informative, multi-modal approach to understanding the influences of the social environment on biology, In-home interviews were conducted with the women newly diagnosed with breast cancer. As a means to explore the impact of the social environment in disrupting stress responses, saliva samples were collected four times per day for three days following the interview. Breast tumor tissue was collected at the time of surgery. In addition, researchers map the social ecology of the four-block area around each participant？？？s home, noting features known to inhibit or encourage social interaction, including vacant buildings and lots (and their use), the amount of foot traffic, and location of key services in relation to the participant？？？s home. Geo-coded data from the public domain will allow us to measure crime, population density, housing quality, and other features of the participants？？？ neighborhoods. Relationships among the geo-coded public data, observer collected neighborhood variables, psychosocial data collected from interviews, and biological specimens were analyzed.
RESULTS: Women in the study exhibited high rates of felt loneliness and higher rates of sexual assault than previously reported for African-American women. Women also exhibited high rates of depression compared to those in prior studies of women with invasive breast cancer. We found that felt loneliness, depression, and sexual assault were strongly correlated with one another and seem to form a ？？？psychosocial suite？？？ of social and traumatic variables that connects the neighborhood- level variables to stress hormone response. Cluster analysis of the diurnal salivary cortisol data revealed two clusters, one with a flat pattern and a more typical pattern. We were able to predict into which group the women fall, using logistic regression analysis, with number of crimes that occurred that year in a quarter-mile buffer zone constructed around each woman？？？s home and psychological response as predictors. Additional analyses reveal that nighttime rise in salivary cortisol can be predicted by crimes and depression. In preliminary analyses of constructing and analyzing our final, inclusive multi-level models, we are able to predict hormone receptor status from social and psychological variables. Implications: Preliminary findings from our studies suggest biological processes are impacted by social environmental factors in which felt loneliness and depression may be pathways through which the social environment ？？？gets under the skin.？？？ Identifying the causal chain from the social environment to disease will shed light on the social structural conditions that must be targeted to reduce overall mortality from the disease, as well as the disparate outcomes between African-American and white women.
Breast Cancer and Social Interactions: Identifying Multiple Environments that Regulate Gene Expression
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- NIGMS-NSF Briefing on Blue Waters High-Performance Computing Opportunities
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- - National Institute of General Medical Sciences (U.S.) (2010/11/18)
- - Category : Special
- Drs. Jeremy Berg (Director, NIGMS), Stephan Meacham (Program Director, NSF), Eric Jakobsson (University of Illinois), Thom Dunning (University of Illinois) and John Moult (University of Maryland) will lead a virtual workshop to discuss opportunities for scientists to access resources of the NSF-funded Blue Waters petascale computing system.
http://www.nigms.nih.gov/bluewaters
NIGMS-NSF Briefing on Blue Waters High-Performance Computing Opportunities
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- Active Shooter
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- - Ritch, John.
National Institutes of Health (U.S.) (2010/11/18) - - Category : Special
- - Ritch, John.
- ？？？Shots Fired？？？; Surviving an Active Shooter in the Workplace discusses the very rare, but deadly event when an armed person, without warning, begins shooting in the workplace. There are many things we can and should do to adequately prepare for such an unlikely event. Your survival depends on increasing your awareness and individual, decisive action. This program will help enable you to do just that.
Active Shooter
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- Intracellular lipid trafficking and organelle biogenesis
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- - Prinz, William.
National Institutes of Health (U.S.) (2010/11/18) - - Category : NIH Directors Seminars
- - Prinz, William.
- 2008-2009 Directors Seminar Series
For more information, visit
http://www.nih.gov/about/director/dirsem.htm
Intracellular lipid trafficking and organelle biogenesis
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- CFC Raffle Drawing (NIH-Only)
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- - John Burke (2010/11/18)
- - Category : NIH Only
- CFC will draw names of donors and keyworkers in order to raffle donated prizes
CFC Raffle Drawing (NIH-Only)
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- Molecular neurobiology of social bonding: Implications for autism spectrum disorders
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- - Larry Young, Ph.D. (2010/11/18)
- - Category : Neuroscience
- Dr. Young？？？s laboratory investigates the molecular and neuroendocrine mechanisms by which neuropeptides and neuropeptide receptors regulate social behaviors. They use a range of techniques ranging from transgenics, viral vector gene transfer, and promoter analysis to examine the mechanisms underlying social behaviors such as affiliation, pair bonding and social recognition in rodents. They have made groundbreaking discoveries relating oxytocin and vasopressin to social behavior in various rodents.
Dr. Young？？？s lab website: http://research.yerkes.emory.edu/Young/research.html
NIH Neuroscience Seminar Series
Molecular neurobiology of social bonding: Implications for autism spectrum disorders
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- Stalking the Crooked Molecule *a.k.a. Translational Research
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- - Robert Innis, MD, PhD (2010/11/18)
- - Category : Special
- Presentation by Candidate for NIMH-DIRP Mood and Anxiety Disorders Program Director
Stalking the Crooked Molecule *a.k.a. Translational Research
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- CC Grand Rounds: (1) Human Subjects Research and the Internet Era (2) Updates on Therapies for Hairy Cell Leukemia
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- - NIH Clinical Center (2010/11/18)
- - Category : Clinical Center Grand Rounds
- Robert Martensen, MD, PhD,
Director, Office of History and Museum, NIH
Robert Kreitman, MD,
Chief, Clinical Immunotherapy Section, Laboratory of Molecular Biology, NCI
For more information, visit
http://www.cc.nih.gov/about/news/grcurrent.html
CC Grand Rounds: (1) Human Subjects Research and the Internet Era (2) Updates on Therapies for Hairy Cell Leukemia
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- Wrong Place, Wrong Time: Understanding Trauma and Violence in the Lives of Young Black Men
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- - Dr. John Rich (2010/11/18)
- - Category : Wednesday Afternoon Lectures
- Violence is epidemic in urban communities and has a disproportionate impact on African American men. In-depth qualitative interviews with young victims of violence reveal both the deep scars of early adversity as well as the persistent physical and psychological scars that result from violent injury. The stories that emerge from their traumatic experiences defy the often simplistic and stereotypical images held by providers and the public at large. In this presentation, we will examine the narratives of young victims as a means to uncover new, trauma-informed approaches to addressing and preventing the causes and consequences of urban violence.
The NIH Directors Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.
Wrong Place, Wrong Time: Understanding Trauma and Violence in the Lives of Young Black Men