전체 8345
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- NIH Senior Leadership Program Orientation (NIH-Only)
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- - Liz Rowe (2010/11/18)
- - Category : NIH Only
- Program One Orientation
NIH Senior Leadership Program Orientation (NIH-Only)
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- National Advisory Allergy and Infectious Diseases Council - February 2010 (NIH-Only)
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- - NIAID (2010/11/18)
- - Category : NIAID Council (NIH Only)
- The NAAIDC provides second level peer review of grant applications and discusses concept clearances and other matters pertaining to grant applications for NIAID. Their website offers information about meeting dates, council members, and has an archive of past meeting minutes. At each meeting, Dr. Anthony Fauci, NIAID Director, presents information about the Institute, including new staff, status of the budget, status of research and other areas of interest to the council. A guest speaker also does a presentation. At the February 1, 2010, meeting, Dr. Tony Scarpa will speak on the status of the new peer review system.
National Advisory Allergy and Infectious Diseases Council - February 2010 (NIH-Only)
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- From Impulsivity to Compulsivity: Neural and Neurochemical Basis
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- - Robbins, Trevor W.
National Institutes of Health (U.S.) (2010/11/18) - - Category : Neuroscience
- - Robbins, Trevor W.
- Research in Dr. Robbins lab spans the areas of cognitive neuroscience, behavioral neuroscience and psychopharmacology. Main work focuses on the functions of the frontal lobes of the brain and their connections with other regions. These brain systems are relevant to such psychiatric and neurological disorders as Parkinson？？？s and Huntington？？？s disease, dementia, schizophrenia, depression, drug addiction, obsessive-compulsive disorder and attention deficit/hyperactivity disorder, as well as frontal lobe injury. Dr. Robbins lab uses a variety of methods for studying these systems, including sophisticated psychological paradigms for investigating cognitive functions and impulsivity in both normal subjects and patients; these include the computerized CANTAB battery. Also employed is MRI or PET to determine where in the human brain various cognitive operations are carried out. They are also interested in establishing how drugs work to produce changes in brain chemistry, and how these affect behavior.
NIH Neuroscience Seminar Series
From Impulsivity to Compulsivity: Neural and Neurochemical Basis
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- AIDS Research Advisory Committee Meeting - February 2010 (NIH-Only)
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- - National Institute of Allergy and Infectious Diseases (NIAID) (2010/11/18)
- - Category : AIDS Research Advisory Committee (NIH Only)
- This is the joint meeting of the NIAID Council AIDS Subcommittee and the AIDS Research Advisory Committee.
For more information, visit
http://www3.niaid.nih.gov/about/overview/councilcommittees/arac.htm
AIDS Research Advisory Committee Meeting - February 2010 (NIH-Only)
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- From Comprehensive Genomics to the Discovery of New Therapeutic Targets in High Risk Acute Lymphoblastic Leukemia - The Impact of Race and Outcome: An Update of the NCI TARGET Project in High Risk ALL (NIH-Only)
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- - Cheryl L. Willman, M.D. (2010/11/18)
- - Category : NCI CCR Grand Rounds (NIH Only)
- NCI？？？s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians proposed by members of the CCR Grand Rounds Planning Committee and others within the CCR community and approved by the CCR Office of the Director. Lectures occur every Tuesday from 8:00 to 9:00 a.m. in Lipsett Amphitheater in the Clinical Center building on the NIH campus September through July with exceptions around holidays and major cancer meetings. The lecture schedule is posted on various calendars of events, including at the following link: http://bethesdatrials.cancer.gov/health-care-professionals/grand-rounds.aspx.
From Comprehensive Genomics to the Discovery of New Therapeutic Targets in High Risk Acute Lymphoblastic Leukemia - The Impact of Race and Outcome: An Update of the NCI TARGET Project in High Risk ALL (NIH-Only)
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- NIH State-of-the-Science Conference: Enhancing Use and Quality of Colorectal Cancer Screening - Day 1
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- - National Cancer Institute Office of Medical Applications of Research, NIH (2010/11/18)
- - Category : Conferences
- Colorectal cancer (CRC) is the second-leading cause of cancer-related deaths in the United States. But, over half the people at average risk for the disease do not take advantage of screening tests such as fecal occult blood testing, sigmoidoscopy, or colonoscopy. Be part of a pivotal discussion that will help answer critical questions related to enhancing the use and quality of CRC screening.
http://consensus.nih.gov/2010/colorectal.htm
NIH State-of-the-Science Conference: Enhancing Use and Quality of Colorectal Cancer Screening - Day 1
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- Mining Data from Genome Browsers
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- - Wolfsberg, Tyra.
National Institutes of Health (U.S.) (2010/11/18) - - Category : Current Topics in Genome Analysis
- - Wolfsberg, Tyra.
- Current Topics in Genome Analysis
Mining Data from Genome Browsers
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- Swine and other Flues: An Epidemic / Pandemic?
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- - Jeffrey Taubenberger (NIAID), Gary Nabel (NIAID) (2010/11/18)
- - Category : Demystifying Medicine
- The course includes presentation of patients, pathology, diagnosis and therapy in the context of major disease problems and current research. Primarily directed toward Ph.D. students, fellows, and staff, it is also of interest to medical students and clinicians. The course is designed to help bridge the gap between advances in biology and their application to major human diseases. Each session includes clinical and basic science components which are presented by NIH staff and outside invitees.
For more information, visit
http://www1.od.nih.gov/oir/DemystifyingMed
Swine and other Flues: An Epidemic / Pandemic?
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- NIH State-of-the-Science Conference: Enhancing Use and Quality of Colorectal Cancer Screening - Day 2
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- - Sponsored by the National Cancer Institute Office of Medical Applications of Research (2010/11/18)
- - Category : Conferences
- Colorectal cancer (CRC) is the second-leading cause of cancer-related deaths in the United States. But, over half the people at average risk for the disease do not take advantage of screening tests such as fecal occult blood testing, sigmoidoscopy, or colonoscopy. Be part of a pivotal discussion that will help answer critical questions related to enhancing the use and quality of CRC screening.
http://consensus.nih.gov/2010/colorectal.htm
NIH State-of-the-Science Conference: Enhancing Use and Quality of Colorectal Cancer Screening - Day 2
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- Brain and Obesity Lecture - February 2010
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- - David B. Allison, Ph.D. (2010/11/18)
- - Category : Brain & Obesity
- Conjectures on Some Curious Connections Among Social Status, Hunger, Fatness, & Longevity
Brain and Obesity Lecture - February 2010
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- Ethics Rounds: Navigating Mismatches in Patient Preference and Staff Expertise
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- - John Lantos, MD (2010/11/18)
- - Category : Clinical Center Grand Rounds
- John Lantos, MD,
Director, Childrens Mercy Bioethics Center,
Childrens Mercy Hospital, Kansas City, Missouri
For more information, visit
http://www.cc.nih.gov/about/news/grcurrent.html
Ethics Rounds: Navigating Mismatches in Patient Preference and Staff Expertise
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- Stem Cell to T Cell: Molecular Anatomy of Commitment
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- - Dr. Ellen Rothenberg (2010/11/18)
- - Category : Wednesday Afternoon Lectures
- For blood stem cells to generate differentiated progeny, the multipotent cells must traverse a complicated decision tree to determine the pathways their development will take. We know something about the branching structure of these decision trees now. One major branch leads to red blood cell and platelet development, another to phagocytic cells and inflammatory cells, and another to many kinds of lymphocytes. We also know many of the molecular mediators that play important roles in the generation of particular blood cell types, both extracellular signals and transcription factors. However, for the most part characterization of each pathway to date has focused on a given blood cell type in isolation from the others, shedding light on the requirements for differentiation but not providing much insight into lineage choice itself. This gap in knowledge is a concern especially since multipotent cells that have not yet committed to a particular fate are suspended in a state of regulatory instability that is likely to be a hotspot for leukemic transformation.
The early development of T cells provides a particularly clear opportunity to dissect the mechanisms that guide cells through a series of alternative fate decisions and into commitment. In this talk, we will discuss the role of Notch signaling in initiating the T-lineage gene expression program; the stepwise progress of lineage restriction as the cells respond to Notch and endogenous regulators; and the transcription factor interactions in the cells that causally determine these major shifts in lineage identity and survival requirements. The process that the cells undergo involves several ？？？layers？？？ of regulatory change rather than a simple response to a single ？？？master？？？ switch. The talk will review insights from gain- and loss-of-function regulatory perturbations, genome-wide mapping of dynamic epigenetic change, and genetic and biochemical evidence for the identity of newly recognized commitment factors. A key focus is the importance of correctly timed repression, not only of the regulators for alternative fates, but also of the stem-cell regulatory program legacy itself.
The NIH Directors Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.
Stem Cell to T Cell: Molecular Anatomy of Commitment
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- NIH State-of-the-Science Conference: Enhancing Use and Quality of Colorectal Cancer Screening - Day 3
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- - Sponsored by the National Cancer Institute Office of Medical Applications of Research (2010/11/18)
- - Category : Conferences
- Colorectal cancer (CRC) is the second-leading cause of cancer-related deaths in the United States. But, over half the people at average risk for the disease do not take advantage of screening tests such as fecal occult blood testing, sigmoidoscopy, or colonoscopy. Be part of a pivotal discussion that will help answer critical questions related to enhancing the use and quality of CRC screening.
http://consensus.nih.gov/2010/colorectal.htm
NIH State-of-the-Science Conference: Enhancing Use and Quality of Colorectal Cancer Screening - Day 3
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- Substance Abuse and Mental Health Services Administrations (SAMHSA) Fiscal Year 2011 Budget Briefing
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- - SAMHSA Administrator Pam S. Hyde, J.D. (2010/11/18)
- - Category : Special
- SAMHSA？？？s Fiscal Year 2011 budget briefing, delivered by SAMHSA administrator Pam S. Hyde, J.D., in the auditorium of the U.S. Department of Health and Human Services at 200 Independence Ave., S.W., Washington, D.C. 20201. The administrator will be presenting the Presidents proposed budget for SAMHSA and how it aligns with their 10 Strategic Initiatives
Substance Abuse and Mental Health Services Administrations (SAMHSA) Fiscal Year 2011 Budget Briefing
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- NCI Executive Committee Scientific Retreat: "Making Personalized Cancer Medicine a Reality - What Will It Take?" - Day 1 (NIH-Only)
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- - National Cancer Institute (U.S.). Executive Committee. (2010/11/18)
- - Category : NIH Only
- Retreat will focus on the question of what it is going to take to realize the potential of personalized cancer medicine. Robust discussions will range from near term expectations in genomics based medicine to advanced technologies and other concepts that could provide new potentially paradigm-shifting directions for cancer research. The goal for the retreat is to explore ideas, concepts and approaches that could inform the development of NCI？？？s future cancer research portfolio.
NCI Executive Committee Scientific Retreat: "Making Personalized Cancer Medicine a Reality - What Will It Take?" - Day 1 (NIH-Only)
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- Next-Generation Sequencing Technologies
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- - Margulies, Elliott H.
National Institutes of Health (U.S.) (2010/11/18) - - Category : Current Topics in Genome Analysis
- - Margulies, Elliott H.
- Current Topics in Genome Analysis
http://genome.gov/COURSE2010
Next-Generation Sequencing Technologies
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- The Science of Small Clinical Trials Lecture Series: Introduction; Fundamentals (Part 1 of 2)
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- - National Institutes of Health (U.S.). Office of Rare Diseases Research. (2010/11/18)
- - Category : Science of Small Clinical Trials
- Over two lectures, Dr. Day will define/describe basic terms and concepts involved in clinical trials, including randomization, different forms of bias, blinding, the role of placebos, varieties of controls, exploratory data analysis and forms of statistical testing, multiplicity, precision and accuracy, endpoint selection, P-values and confidence limits, repeated measures, stratification, and analysis of covariance; case studies will be presented for Fabrys Disease & Pediatric Inflammatory Bowel Disease.
http://small-trials.keenminds.org/
The Science of Small Clinical Trials Lecture Series: Introduction; Fundamentals (Part 1 of 2)
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- Rethinking Randomized Clinical Trials for Comparative Effectiveness Research: Applications in Obesity and Diabetes
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- - Cizza, Giovanni.
National Institutes of Health (U.S.) (2010/11/18) - - Category : Special
- - Cizza, Giovanni.
- Speakers:
Bryan R. Luce: "Rationale, Need & Opportunity to Improve Operational and Analytical Efficiency and Pragmatism"
Jason Connor: "Bayesian Adaptive Designs in the Dynamic CER Environment to Improve Efficiency & Responsiveness"
J. Jaime Caro: "Using Simulation to Help Plan Pragmatic Trials"
Rethinking Randomized Clinical Trials for Comparative Effectiveness Research: Applications in Obesity and Diabetes
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- CTSA Industry Forum: Promoting Efficient and Effective Collaborations among Academia, Government and Industry - Day 1
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- - National Center for Research Resources (NCRR) (2010/11/18)
- - Category : Conferences
- Join stakeholders from CTSAs, government, industry, academia and nonprofit research communities as they explore current ground-breaking practices and successful management models as ways to streamline the development of new drugs, devices and diagnostics. Participate in interactive breakout sessions to discuss ways to accelerate the discovery and development of new drugs; promote efficient and effective collaborations with the CTSAs, industry and nonprofit organizations; and explore public？？？private partnership opportunities. A networking reception and poster session also are planned.
www.palladianpartners.com/CTSAIndustryForum
CTSA Industry Forum: Promoting Efficient and Effective Collaborations among Academia, Government and Industry - Day 1
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- NCI Executive Committee Scientific Retreat: "Making Personalized Cancer Medicine a Reality - What Will It Take?" - Day 2 (NIH-Only)
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- - National Cancer Institute (U.S.). Executive Committee. (2010/11/18)
- - Category : NIH Only
- Retreat will focus on the question of what it is going to take to realize the potential of personalized cancer medicine. Robust discussions will range from near term expectations in genomics based medicine to advanced technologies and other concepts that could provide new potentially paradigm-shifting directions for cancer research. The goal for the retreat is to explore ideas, concepts and approaches that could inform the development of NCI？？？s future cancer research portfolio.
NCI Executive Committee Scientific Retreat: "Making Personalized Cancer Medicine a Reality - What Will It Take?" - Day 2 (NIH-Only)